Three-dimensional reconstruction of tetraploid<->diploid chimaeric mouse blastocysts
نویسندگان
چکیده
منابع مشابه
Three-dimensional reconstruction of tetraploid<-->diploid chimaeric mouse blastocysts.
Studies of tetraploid<-->diploid (4n<-->2n) mouse chimaeras have demonstrated unequal contributions of 4n cells to different tissues of the midgestation conceptus. Such a pattern has also been reported in chimaeras as early as E3.5d, which show an enhanced contribution of 4n cells to the mural trophectoderm (Everett & West, 1996). In this study, sectioned 4n<-->2n and 2n<-->2n control chimaeric...
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The development during and immediately after the implantation period of 143 tetraploid blastocysts was studied both in vitro and in vivo; 58-7% in vitro and 38-8% in vivo were found to exhibit the changes associated with the early implanting blastocyst, i.e. giant cell transformation of the trophoblast and induction of the decidual cell reaction in the uterus. Of these 38-7% in vitro and 19-4% ...
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Previous studies have shown that tetraploid (4n) cells rarely contribute to the derivatives of the epiblast lineage of mid-gestation 4n<-->2n mouse chimeras. The aim of the present study was to determine when and how 4n cells were excluded from the epiblast lineage of such chimeras. The contributions of GFP-positive cells to different tissues of 4n<-->2n chimeric blastocysts labelled with tauGF...
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Renal function is crucially dependent on renal microstructure which provides the basis for the regulatory mechanisms that control the transport of water and solutes between filtrate and plasma and the urinary concentration. This study provides new, detailed information on mouse renal architecture, including the spatial course of the tubules, lengths of different segments of nephrons, histotopog...
متن کاملDevelopment of cytochalasin in B-induced tetraploid and diploid/tetraploid mosaic mouse embryos.
By subjecting ¥x (CBA x C57/BL) x A eggs at the time of 2nd cleavage to 10 /tg/ml of cytochalasin B (CB), tetraploidy was produced in 52 % of 2-cell eggs and 35 % of 3-cell eggs. 2n/4n mosaic embryos were produced from 2-, 3and 4-cell eggs and amounted to 20 % of all treated eggs. 80 % of tetraploid embryos developed in vitro into regular blastocysts with half the cell number of control diploid...
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ژورنال
عنوان ژورنال: Journal of Anatomy
سال: 2000
ISSN: 0021-8782,1469-7580
DOI: 10.1046/j.1469-7580.2000.19630341.x